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Douglas Laboratories - ORANGE-CHEW (500 MG.)
ORANGE-CHEW (500 MG.)
Price: $10.20
Description

ORANGE-CHEW (500 MG.)


Size: 100
See Also Products
Functions: 

Vitamin C (ascorbic acid) has numerous biological functions. Foremost, it is essential for the synthesis of collagen and glycosaminoglycans which are the building materials of all connective tissues, such as skin, blood vessels, tendons, joint cartilage and bone. Vitamin C is the required coenzyme for two groups of enzymes that catalyze the crosslinking of collagen fibers - lysyl hydroxylases and prolyl hydroxylases. As such, vitamin C is essential for normal wound healing and capillary health. It also participates in the biosynthesis of carnitine, serotonin, and certain neurotransmitters, including norepinephrine. Vitamin C is among the most powerful antioxidants in humans and animals. It is a water-soluble, chain- breaking antioxidant that reacts directly with superoxide, hydroxyl radicals, and singlet oxygen. Laboratory studies show that vitamin C completely protects lipids in plasma and low-density lipoprotein (LDL) against atherogenic peroxidative damage. In addition, vitamin C interacts with glutathione and alpha-lipoic acid, and regenerates vitamin E. The antioxidant functions of vitamin C appear to have clinical significance in providing protection from free radical damage to the eyes, lungs, blood and the immune system. Vitamin C is absorbed in the small intestine by a sodium-dependent transport process that is intake dependent. At normal dietary intakes of 60 to 100 mg, up to 80 or 90% of the vitamin C is absorbed. At higher intakes, absorption becomes less efficient. Absorption efficiency and vitamin C utilization may be greatly enhanced during conditions of physiological stress, such as trauma or infection. Maximal absorption is attained by the ingestion of several doses spaced throughout the day rather than in one, larger dose.

Item type: 
Other Nutritional Supplements
Indications: 

Orange-Chewï›› 500mg may be a useful dietary supplement for those who wish to increase their daily intake of this important antioxidant vitamin in a pleasant tasting chewable form.

Formula: 

7955

Suggested usage: 

Adults take 1 tablet daily or as directed by physician.

Warnings/Side effects: 

No adverse effects have been reported.

Storage: 

Store in a cool, dry place, away from direct light. Keep out of reach of children.

References: 

Allard JP, Aghdassi E, Chau J, et al. Effects of vitamin E and C supplementation on oxidative stress and viral load in HIV-infected subjects. Aids 1998;12:1653-9. Anderson JW, Gowri MS, Turner J, et al. Antioxidant supplementation effects on low-density lipoprotein oxidation for individuals with type 2 diabetes mellitus. J Am Coll Nutr 1999;18:451-61. Campbell JD, Cole M, Bunditrutavorn B, et al. Ascorbic acid is a potent inhibitor of various forms of T cell apoptosis. Cell Immunol 1999;194:1-5. de la Fuente M, Ferrandez MD, Burgos MS, et al. Immune function in aged women is improved by ingestion of vitamins C and E. Can J Physiol Pharmacol 1998;76:373-80. Del Rio M, Ruedas G, Medina S, et al. Improvement by several antioxidants of macrophage function in vitro. Life Sci 1998;63:871-81. Hughes DA. Effects of dietary antioxidants on the immune function of middle-aged adults. Proc Nutr Soc 1999;58:79-84. Paolisso G, Tagliamonte MR, Rizzo MR, et al. Oxidative stress and advancing age: results in healthy centenarians. J Am Geriatr Soc 1998;46:833-8. Douglas Laboratories ® (continued on reverse) Product Data Douglas Laboratories ® Park E, Wagenbichler P, Elmadfa I. Effects of multivitamin/mineral supplementation, at nutritional doses, on plasma antioxidant status and DNA damage estimated by sister chromatid exchanges in lymphocytes in pregnant women. Int J Vitam Nutr Res 1999;69:396-402. Schwager J, Schulze J. Modulation of interleukin production by ascorbic acid. Vet Immunol Immunopathol 1998;64:45-57. Simon JA, Grady D, Snabes MC, et al. Ascorbic acid supplement use and the prevalence of gallbladder disease. Heart & Estrogen- Progestin Replacement Study (HERS) Research Group. J Clin Epidemiol 1998;51:257-65. Victor VV, Guayerbas N, Puerto M, et al. Ascorbic acid modulates in vitro the function of macrophages from mice with endotoxic shock. Immunopharmacology 2000;46:89-101.

Manufactured: 

Manufactured by Douglas Laboratories 600 Boyce Road Pittsburgh, PA 15205 800-245-4440

Information: 

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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